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Invitrogen™ Mosunetuzumab Humanized Recombinant Human Monoclonal Antibody

Description
Endotoxin level < 0.01EU/μg by LAL method Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
Mosunetuzumab is an investigational, humanized, T-cell bispecific antibody designed to engage T cells and redirect their cytotoxic activity against malignant B cells. Mosunetuzumab simultaneously binds to CD3 epsilon (CD3epsilon), a component of the T-cell receptor (TCR) complex, and to CD20, a B-cell surface protein expressed in a majority of B-cell malignancies. This results in crosslinking of the TCR, inducing downstream signaling events that lead to B-cell killing.
Specifications
Specifications
| Antigen | Mosunetuzumab Humanized |
| Applications | ELISA, SDS-Page |
| Classification | Recombinant Monoclonal |
| Concentration | 2.7 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene Alias | BTCT4465A; Cevostamab; Lunsumio; RG-7828; RO7030816 |
| Host Species | Human |
| Immunogen | Human CD3E/MS4A1/CD20. |
| Purification Method | Protein A/G |
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