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Invitrogen™ Monkey IL-6R ELISA Kit

Product Code. 17135809
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Quantity:
10 x 96 Tests
5 x 96 Tests
96 Tests
Unit Size:
Each
Pack of 10
Pack of 96
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Product Code. 17135809

Brand: Invitrogen™ EP14RBX5

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ELISA

Monkey IL-6R quantitates monkey IL-6R in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant monkey IL-6R.

Interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor. This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number CD126; CD126 antigen; gp80; IL-6 Receptor; il-6 receptor alpha; IL-6 receptor alpha chain; IL-6 receptor subunit alpha; IL6Q; Il6r; IL-6 R; IL-6 R 1; IL-6 R subunit alpha; IL6R1; IL-6 R-1; Il6ra; IL-6 RA; IL-6 R-alpha; IL6RQ; ILN; Interleukin; interleukin 6 receptor; interleukin 6 receptor, alpha; interleukin-6 receptor subunit alpha; Membrane glycoprotein 80; MGC104991
Assay Range 12 to 3,000 pg/mL
Assay Sensitivity 12 pg/mL
Conjugate HRP
Product Type ELISA
Sample Type Plasma, Serum, Supernatant
For Use With (Equipment) Colorimetric Microplate Reader
Interassay CV <12%
Intraassay CV <10
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Label or Dye HRP
Quantity 5 x 96 Tests
Regulatory Status RUO
Sample Volume Plasma 50 μL, Serum 50 μL, Supernatant 50 μL
Storage Requirements 2°C to 8°C
Target IL-6 Receptor (CD126)
Test Time 1 hrs 20 mins
Total Assay Time 4 hrs 45 mins
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