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Momelotinib, MedChemExpress

Product Code. 16461006
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Product Code. 16461006 Supplier Medchem Express Supplier No. HY10961

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Description

MedChemExpress Momelotinib (CYT387) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50a of 11 nM and 18 nM,respectively. CYT387 shows much less activity against JAK3.

Momelotinib (CYT387) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50a of 11 nM and 18 nM,respectively. CYT387 shows much less activity against JAK3.

Specifications

Chemical Name or Material Momelotinib
CAS 1056634-68-4
Color Yellow
Purity Grade Notes Research
Molecular Formula C23H22N6O2
Quantity 200 mg
Synonym CYT387
Solubility Information DMSO : 20.83 mg/mL (50.26 mM; ultrasonic and warming and heat to 80°C)
SMILES O=C(C1=CC=C(C2=NC(NC3=CC=C(N4CCOCC4)C=C3)=NC=C2)C=C1)NCC#N
Molecular Weight (g/mol) 414.46
Formula Weight 414.46
Percent Purity 96.95%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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