Invitrogen™ Thapsigargin

Tumor promoter

Brand:  Invitrogen™ T7459

Product Code. 11570796

Description

Thapsigargin is a naturally occurring sesquiterpene lactone isolated from the umbelliferous plant Thapsia garganica. This tumor promoter releases Ca²⁺⁺ from intracellular stores by specifically inhibiting the endoplasmic reticulum Ca²⁺⁺-ATPase. It does not directly affect plasma membrane Ca²⁺⁺-ATPases, Ins 1,4,5-P₃ production or protein kinase C activity.

Cell Analysis, Cell Structure, Cellular Imaging, Immunofluorescence (IF), Immunofluorescence Staining and Detection, Receptors

Specifications

• Quantity: 20 x 50 μg
• Label Type: Unlabeled
• Product Type: Inhibitor

• Shipping Condition: Room Temperature
• Molecular Formula: C34H50O12

Safety and Handling

Product Identifier

• Thapsigargin

Signal Word

• Danger

Hazard Category

• Serious eye damage/eye irritation Category 2
• Respiratory sensitiser Category 1
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
• H335-May cause respiratory irritation.

Precautionary Statement

• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P337+P313-If eye irritation persists: Get medical advice/attention.

Supplemental information

• MIXTURE LIST-Contains : Thapsigargin

For Research Use Only. Not for use in diagnostic procedures.