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Invitrogen™ Thapsigargin
Description
Thapsigargin is a naturally occurring sesquiterpene lactone isolated from the umbelliferous plant Thapsia garganica. This tumor promoter releases Ca2++ from intracellular stores by specifically inhibiting the endoplasmic reticulum Ca2++-ATPase. It does not directly affect plasma membrane Ca2++-ATPases, Ins 1,4,5-P3 production or protein kinase C activity.
Cell Analysis, Cell Structure, Cellular Imaging, Immunofluorescence (IF), Immunofluorescence Staining and Detection, Receptors
Order Info
Shipping Condition: Room temperature
Specifications
Specifications
| Quantity | 20 x 50 μg |
| Shipping Condition | Room Temperature |
| Label Type | Unlabeled |
| Molecular Formula | C34H50O12 |
| Product Type | Inhibitor |
Safety and Handling
- Thapsigargin
- Danger
- Serious eye damage/eye irritation Category 2
- Respiratory sensitiser Category 1
- Skin corrosion/irritation Category 2
- Specific target organ toxicity Category 3
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
- H335-May cause respiratory irritation.
- P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
- P302+P352-IF ON SKIN: Wash with plenty of water/soap.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P337+P313-If eye irritation persists: Get medical advice/attention.
- MIXTURE LIST-Contain: Thapsigargin
For Research Use Only. Not for use in diagnostic procedures.
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