Invitrogen™ Brefeldin A (from Penicillium brefeldianum)

Product Code. 11584197

Brand: Invitrogen™ B7450

Description

The fungal metabolite brefeldin A (BFA) has multiple targets in cells and has proven valuable for dissecting the cellular processes, including vesicle formation and kinesin distribution, involved in exporting newly synthesized proteins.

The fungal metabolite brefeldin A (BFA) has multiple targets in cells and has proven valuable for dissecting the cellular processes, including vesicle formation and kinesin distribution, involved in exporting newly synthesized proteins. We are pleased to offer the natural brefeldin A isolated from Penicillium brefeldianum. Exposing cells to BFA causes a distortion in intracellular protein traffic from the ER to the Golgi apparatus and the eventual loss of Golgi apparatus morphology; removal of BFA completely reverses these effects. BFA also alters the morphology of endosomes and lysosomes.

Dissolve in high-quality anhydrous DMSO or ethanol to prepare a stock concentration up to 1 mM.

Order Info

Shipping Condition: Room Temperature

Specifications

• Quantity: 5 mg
• Shipping Condition: Room Temperature
• Label Type: Unlabeled
• Molecular Formula: C₁₆H₂₄O₄
• Physical Form: Powder
• Product Type: Sphingolipid
• Molecular Weight (g/mol): 280.36

Safety and Handling

Product Identifier

• Brefeldin A (from Penicillium brefeldianum)

Signal Word

• Warning

Hazard Category

• Acute toxicity Category 4

Hazard Statement

• H302-Harmful if swallowed.

Precautionary Statement

• P264-Wash hands thoroughly after handling.
• P270-Do not eat, drink or smoke when using this product.
• P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
• P330-Rinse mouth.

Supplemental information

• MIXTURE LIST-Contains : brefeldin A

For Research Use Only. Not for use in diagnostic procedures.