MMP11 Mouse anti-Human, Clone: SL3.05, Abnova™

Mouse monoclonal antibody raised against human MMP11

Brand:  Abnova MAB12543.50uL

Product Code. 16081156

Description

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq]

Specifications

• Antigen: MMP11
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200) Immunoprecipitation Western Blot The optimal working dilution should be determined by the end user.
• Gene Alias: SL-3/ST3/STMY3
• Host Species: Mouse
• Purification Method: Protein G purification
• Regulatory Status: RUO
• Gene ID (Entrez): 4320
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1 κ

• Applications: Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
• Clone: SL3.05
• Description: Mouse monoclonal antibody raised against human MMP11
• Formulation: In PBS, pH 7.4 (0.2% BSA, 0.09% sodium azide).
• Gene Symbols: MMP11
• Immunogen: Recombinant protein corresponding to human MMP11.
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid