Invitrogen™ MMP10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA529746

Product Code. 13484007

Description

Recommended positive controls: HepG2, human MMP10-transfected 293T, HepG2 conditioned medium. Predicted reactivity: Mouse (83%), Rat (80%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

MMP10 belongs to the matrix metalloproteinase family, and is generally secreted in its pro form, which is further modified by extracellular proteinases. As a metalloproteinase, MMP10 requires zinc and calcium as cofactors for activity. It is involved in the activation of pro-collagenase, catabolism of collagen, degradation of fibronectin, and tissue remodeling. In humans, the gene MMP10 located on chromosome 11.

Specifications

• Antigen: MMP10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MMP10
• Gene Alias: AV377895; matrix metallo protease; matrix metallopeptidase 10; matrix metallopeptidase 10 (stromelysin 2); matrix metalloprotease 10; matrix metalloproteinase 10; matrix metalloproteinase 10 (stromelysin 2); matrix metalloproteinase-10; MMP; Mmp10; MMP-10; MMPs; SL-2; STMY2; stromelysin 2; stromelysin-2; Transformation-associated protein 34A; transin 2; transin-2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4319
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P09238
• Gene Symbols: MMP10
• Immunogen: Recombinant protein encompassing a sequence within the center region of human MMP10. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG