Invitrogen™ MMP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA527210

Product Code. 13471257

Description

Recommended positive controls: Raji, HUVEC, dermal fibroblast cells. Predicted reactivity: Pig (90%), Rabbit (86%), Bovine (83%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: MMP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MMP1
• Gene Alias: 22 kDa interstitial collagenase; 27 kDa interstitial collagenase; CLG; CLGN; Collagenase; collagenase-like A; fibroblast collagenase; Interstitial collagenase; interstitial collagenase A; matrix metallo protease; matrix metallopeptidase 1; matrix metallopeptidase 1 (interstitial collagenase); matrix metallopeptidase 1a; matrix metallopeptidase 1a (interstitial collagenase); matrix metalloprotease 1; matrix metalloproteinase 1; matrix metalloproteinase 1a (interstitial collagenase); Matrix metalloproteinase1; Matrix metalloproteinase-1; Matrix metalloproteinase-1a; McolA; Mcol-A; MMP; MMP1; MMP-1; Mmp1a; MMP-1a; MMPs
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4312, 83995
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.0 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P03956, Q9EPL5
• Gene Symbols: MMP1, Mmp1a
• Immunogen: Recombinant protein encompassing a sequence within the center region of human MMP1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG