Invitrogen™ MMACHC Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA587836

Product Code. 16596211

Description

Immunogen sequence: LKPFLQSCHL RMLTDPVDQC VAYHLGRVRE SLPELQIEII ADYEVHPNRR PKILAQTAAH VAGAAYYYQR QDVEADPWGN QRISGVCIHP RFGGWFAIRG VVLLPGIEVP DLPPRKPHDC VPTRADRIAL LEGFNFHWRD WTYRDAVTPQ ERYSEEQKAY FSTPPAQRLA LLGLAQPSEK PSSPSPDLPF TTPAPKKPGN PSRARSWLSP RVSPPASPGP; Positive Samples: Raji, Jurkat, Mouse kidney, Rat brain; Cellular Location: Cytoplasm.

The exact function of the MMACHC protein is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC.

Specifications

• Antigen: MMACHC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MMACHC
• Gene Alias: 1810037K07Rik; cblC; Cyanocobalamin reductase (cyanide-eliminating); methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria; methylmalonic aciduria and homocystinuria type C protein; Methylmalonic aciduria and homocystinuria type C protein homolog; methylmalonic aciduria cblC type, with homocystinuria; Mmachc; RGD1310806; RP11-291L19.3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 25974, 313520, 67096
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 3.89 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9CZD0, Q9Y4U1
• Gene Symbols: MMACHC
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 63-282 of human MMACHC (NP_0563212).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG