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Invitrogen™ MMACHC Polyclonal Antibody
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Product Code. 16596211
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Quantity:
100 μL
Unit Size:
100µL
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16596211 100 μL 100µL
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Product Code. 16596211 Supplier Invitrogen™ Supplier No. PA587836

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LKPFLQSCHL RMLTDPVDQC VAYHLGRVRE SLPELQIEII ADYEVHPNRR PKILAQTAAH VAGAAYYYQR QDVEADPWGN QRISGVCIHP RFGGWFAIRG VVLLPGIEVP DLPPRKPHDC VPTRADRIAL LEGFNFHWRD WTYRDAVTPQ ERYSEEQKAY FSTPPAQRLA LLGLAQPSEK PSSPSPDLPF TTPAPKKPGN PSRARSWLSP RVSPPASPGP; Positive Samples: Raji, Jurkat, Mouse kidney, Rat brain; Cellular Location: Cytoplasm.

The exact function of the MMACHC protein is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MMACHC
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 3.89 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MMACHC
Gene Accession No. Q9CZD0, Q9Y4U1
Gene Alias 1810037K07Rik; cblC; Cyanocobalamin reductase (cyanide-eliminating); methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria; methylmalonic aciduria and homocystinuria type C protein; Methylmalonic aciduria and homocystinuria type C protein homolog; methylmalonic aciduria cblC type, with homocystinuria; Mmachc; RGD1310806; RP11-291L19.3
Gene Symbols MMACHC
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 63-282 of human MMACHC (NP_0563212).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25974, 313520, 67096
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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