Invitrogen™ MLK1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA533917

Product Code. 15302431

Description

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Hamster, Rabbit, Pig (100%).

MAP3K9 (MLK1) is a serine/threonine protein kinase that functions in the MAP kinase pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.

Specifications

• Antigen: MLK1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MAP3K9
• Gene Alias: E130314H24Rik; Map3k9; MEKK9; mitogen activated protein kinase kinase kinase 9; mitogen-activated protein kinase kinase kinase 9; Mixed lineage kinase 1; mixed lineage kinase 1 (tyr and ser/thr specificity); mixed-lineage kinase 1; MLK1; Prke1; RGD1562149
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100155753, 100341731, 100762934, 338372, 4293
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: P80192, Q3U1V8
• Gene Symbols: MAP3K9
• Immunogen: Synthetic 15 amino acid peptide from internal region of human MAP3K9.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rabbit, Hamster, Pig
• Product Type: Antibody
• Isotype: IgG