Invitrogen™ MLH3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA542166

Product Code. 15585292

Description

Peptide sequence: SMQVLQQVDN KFIACLMSTK TEENGEADSY EKQQAQGSGR KKLLSSTLIP Sequence homology: Human: 100%.

This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

Specifications

• Antigen: MLH3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MLH3
• Gene Alias: AV125803; BB126472; CAE; CAE1; cell surface glycoprotein; connexin 50; connexin-50; CTRCT1; CX50; CZP1; DNA mismatch repair protein Mlh3; gap junction alpha 8; gap junction alpha-8 protein; gap junction membrane channel protein alpha-8; gap junction protein alpha 8; gap junction protein alpha 8 50kDa; GJA8; HNPCC7; lens fiber protein MP70; lens intrinsic membrane protein MP70; MGC138372; MLH3; MP70; mutL homolog 3; mutL homolog 3 (E coli); MutL protein homolog 3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27030
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9UHC1
• Gene Symbols: MLH3
• Immunogen: Synthetic peptide directed towards the middle region of human MLH3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG