ACROBiosystems Cynomolgus PVRIG Protein, Fc Tag

Product Code. 16497989

Brand: ACROBiosystems PVGC52591mg

Description

Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 40.1 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Specifications

• Accession Number: XP_005549281.1
• Molecular Weight (g/mol): 40.1 kDa
• Quantity: 1 mg
• Source: Cynomolgus PVRIG, Fc Tag (PVG-C5259) is expressed from human 293 cells (HEK293). It contains AA Thr 41 - Asp 171 (Accession # A0A2K5WVV8-1).
• Immunogen: Thr 41 - Asp 171
• Storage Requirements: -20°C
• Gene Alias: C7orf15,C7orf15MGC138295,CD112R,MGC104322,MGC138297,MGC2463,PVRIG,CD112 receptor
• Common Name: PVRIG
• Conjugate: Unconjugated
• Species: Cynomolgus Monkey
• Protein Tag: Fc Tag
• Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
• Endotoxin Level: Less than 1.0 EU / μg by the LAL method.
• Expression System: HEK293
• Form: Powder
• Protein Subtype: Immune Checkpoint Proteins
• Purity or Quality Grade: >95% as determined by SDS-PAGE