missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Cell Culture Media, Supplements, and Reagents
  4. Cell Culture Reagents, Antibiotics and Supplements
  5. Antibiotics
  6. ML221, MedChemExpress

ML221, MedChemExpress

Product Code. 16496537
Encompass_Preferred
Change view
Click to view available options
Quantity:
5 mg
10 mg
25 mg
50 mg
100 mg
Unit Size:
100mg
10mg
25mg
50mg
5mg
5 product options available for selection
Product selection table with 5 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
16496537 5 mg 5mg
16472866 25 mg 25mg
16434866 100 mg 100mg
16433818 10 mg 10mg
16410197 50 mg 50mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 5 options available.
5 options
This item is not returnable. View return policy
Product Code. 16496537 Supplier Medchem Express Supplier No. HY103254

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

MedChemExpress ML221 is a potent apelin (APJ) functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s of 0.70 μM in the cAMP assay, and 1.75 μM in the β-arrestin assay, and EC80 of 10 nM in both assays.

ML221 is a potent apelin (APJ) functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s of 0.70 μM in the cAMP assay, and 1.75 μM in the β-arrestin assay, and EC80 of 10 nM in both assays.

Specifications

Chemical Name or Material ML221
Physical Form Solid
CAS 877636-42-5
Color Off-White
Quantity 5 mg
Purity Grade Notes Research
Molecular Formula C17H11N3O6S
For Use With (Application) Neuroscience-Neuromodulation
Solubility Information DMSO : ≥ 31 mg/mL (80.45 mM)
SMILES O=C1C=C(CSC2=NC=CC=N2)OC=C1OC(C3=CC=C([N+]([O-])=O)C=C3)=O
Molecular Weight (g/mol) 385.35
Formula Weight 385.35
Percent Purity 98.0%
Grade Research
Show More Show Less

Research purposes only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.