Invitrogen™ MKP4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA582081

Product Code. 16379044

Description

Immunogen sequence: ECPHLCETSL AGRAGSSMAP VPGPVPVVGL GSLCLGSDCS DAESEADRDS MSCGLDSEGA TPPPVGLRAS FPVQILPNLY LGSARDSANL ESLAKLGIRY ILNVTPNLPN FFEKNGDFHY KQI Highest antigen sequence indentity to the following orthologs: Mouse - 82%, Rat - 80%.

Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), VHR, PAC1, MKP-2, hVH-3 (B23), hVH-5, MKP-3, MKP-X and MKP-4.

Specifications

• Antigen: MKP4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DUSP9
• Gene Alias: dual specificity phosphatase 9; dual specificity protein phosphatase 9; dual-specificity MAP kinase phosphatase 4; Dusp4; DUSP9; MAP kinase phosphatase 4; mitogen-activated protein kinase phosphatase 4; MKP4; MKP-4; Mpk4; Pyst3; serine/threonine specific protein phosphatase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1852
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q99956
• Gene Symbols: DUSP9
• Immunogen: Recombinant protein corresponding to Human DUSP9. Recombinant protein control fragment (Product #RP-92206).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG