Invitrogen™ MKL2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA569702

Product Code. 15838113

Description

This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%.

Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF regulates the transient response of several muscle genes in response to growth factors and recruits accessory myogenic factors to activate these muscle genes. SRF is required for the formation of vertebrate mesoderm leading to the origin of the cardiovascular system. Myocardin, in association with SRF in cardiac muscle cells, activates cardiac muscle promoters. Myocardin-related transcription factors A and B (MRTF-A and MRTF-B) interact with SRF and act as stimulators for its transcriptional activity. MRTF-B is crucial for skeletal myogenic differentiation.

Specifications

• Antigen: MKL2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Mkl2
• Gene Alias: CTA-276F8.1; ENSMUSG00000075401; gene trap insertion site 4-1; Gt4-1; KIAA1243; Megakaryoblastic leukemia 2; megakaryoblastic leukemia 2 protein; mKIAA1243; MKL/myocardin like 2; MKL/myocardin-like 2; MKL/myocardin-like protein 2; MKL1/myocardin like 2; Mkl2; Mrtfb; MRTF-B; myocardin related transcription factor B; myocardin-related transcription factor B; myocardin-related transcription factor B; MKL/myocardin-like protein 2; NPD001; RGD1560833
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100362470
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: 0
• Gene Symbols: Mkl2
• Immunogen: synthetic peptide directed towards the N-terminal region of rat MKL2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG