missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 18024302

Tocris Bioscience™ MK 886

Product Code. 18024302
Click to view available options
Quantity:
2 mg
Unit Size:
2mg
This item is not returnable. View return policy

Product Code. 18024302

Brand: Tocris Bioscience™ 1311/2

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Inhibitor of 5-lipoxygenase-activating protein (FLAP)

MK 886 is a potent inhibitor of 5-lipoxygenase-activating protein (FLAP) (IC50 = 30 nM for inhibition of [125I]-L-691,678 photoaffinity labelling). Inhibits leukotriene biosynthesis (IC50 = 3 nM in human polymorphonuclear leukocytes). Also moderately potent PPARα antagonist (IC50 = 0.5-1 μM). Orally active in vivo.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 1-[(4-Chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-α,α-dimethyl-5-(1-methylethyl)-1H-Indole-2-propanoic acid
CAS 118414-82-7
Quantity 2 mg
Target Lipoxygenase Inhibitors
Molecular Formula C27H34ClNO2S
Purity 98%
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.