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  5. Tocris Bioscience™ Mirtazapine

Tocris Bioscience™ Mirtazapine
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Product Code. 30001439
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Product Code. Quantity unitSize
30001439 10 mg 10mg
18035572 50 mg 50mg
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Product Code. 30001439

Brand: Tocris Bioscience™ 2018/10

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Description

Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant

Mirtazapine is an antidepressant agent; potent 5-HT2, 5-HT3 and histamine H1 receptor antagonist and moderately potent α2-adrenoceptor antagonist (pKi values are 8.05, ∼ 8.1, 9.3 and 6.95 respectively). Enhances noradrenaline (NA) release in rat brain via inhibition of α2-adrenergic autoreceptors and displays only weak affinity for monoamine transporters (pKi values are 5.6, < 5 and < 5.1 for inhibition of NA, dopamine and 5-HT uptake respectively). Increases hippocampal NA and 5-HT levels in rats following systemic administration in vivo.
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Chemical Identifiers

CAS 85650-52-8
Molecular Formula C17H19N3

Specifications

Quantity 10 mg
Formula Weight 265.36
Purity >99%
Molecular Weight (g/mol) 265.36
Chemical Name or Material Mirtazapine
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