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Mirdametinib, MedChemExpress

Product Code. 16454806
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Product Code. 16454806 Supplier Medchem Express Supplier No. HY10254

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Description

MedChemExpress Mirdametinib (PD0325901) is an orally active, selective and non-ATP-competitive MEK inhibitor with an IC50 of 0.33 nM. Mirdametinib exhibits a Kiapp of 1 nM against activated MEK1 and MEK2. Mirdametinib suppresses the expression of p-ERK1/2 and induces apoptosis. Mirdametinib has anti-cancer activity for a broad spectrum of human tumor xenografts.

Mirdametinib (PD0325901) is an orally active, selective and non-ATP-competitive MEK inhibitor with an IC50 of 0.33 nM. Mirdametinib exhibits a Kiapp of 1 nM against activated MEK1 and MEK2. Mirdametinib suppresses the expression of p-ERK1/2 and induces apoptosis. Mirdametinib has anti-cancer activity for a broad spectrum of human tumor xenografts.

Specifications

Chemical Name or Material Mirdametinib
CAS 391210-10-9
Color White
Purity Grade Notes Research
Molecular Formula C16H14F3IN2O4
Quantity 100 mg
Synonym PD0325901 PD325901
Solubility Information DMSO : ≥ 56 mg/mL (116.14 mM)
SMILES O=C(C1=CC=C(C(F)=C1NC2=CC=C(I)C=C2F)F)NOC[C@H](O)CO
Molecular Weight (g/mol) 482.19
Formula Weight 482.19
Percent Purity 99.34%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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