Mirdametinib, MedChemExpress

Artikelnummer. 16454806

Marke: Medchem Express HY10254

Beschreibung

MedChemExpress Mirdametinib (PD0325901) is an orally active, selective and non-ATP-competitive MEK inhibitor with an IC50 of 0.33 nM. Mirdametinib exhibits a Kiapp of 1 nM against activated MEK1 and MEK2. Mirdametinib suppresses the expression of p-ERK1/2 and induces apoptosis. Mirdametinib has anti-cancer activity for a broad spectrum of human tumor xenografts.

Mirdametinib (PD0325901) is an orally active, selective and non-ATP-competitive MEK inhibitor with an IC50 of 0.33 nM. Mirdametinib exhibits a Kiapp of 1 nM against activated MEK1 and MEK2. Mirdametinib suppresses the expression of p-ERK1/2 and induces apoptosis. Mirdametinib has anti-cancer activity for a broad spectrum of human tumor xenografts.

Spezifikation

• Chemical Name or Material: Mirdametinib
• CAS: 391210-10-9
• Color: White
• Purity Grade Notes: Research
• Molecular Formula: C₁₆H₁₄F₃IN₂O₄
• Quantity: 100 mg
• Synonym: PD0325901 PD325901
• Solubility Information: DMSO : ≥ 56 mg/mL (116.14 mM)
• SMILES: O=C(C1=CC=C(C(F)=C1NC2=CC=C(I)C=C2F)F)NOC[C@H](O)CO
• Molecular Weight (g/mol): 482.19
• Formula Weight: 482.19
• Percent Purity: 99.34%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Cancer-Kinase/protease

Research purposes only