Invitrogen™ Mouse MIP-1a (CCL3) ELISA Development Kit (ABTS), PeproTech®

Product Code. 17899015

Brand: Invitrogen™ 900K125

Description

ELISA

Both MIP-1alpha and MIP-1beta are structurally and functionally related CC chemokines. They participate in host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells (e.g. macrophages, lymphocytes and NK cells). While both MIP-1alpha and MIP-1beta exert similar effects on monocytes, their effect on lymphocytes differ; with MIP-1alpha selectively attracting CD8+ lymphocytes, and MIP-1beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1alpha and MIP-1beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1alpha and MIP-1beta are active on human and murine hematopoietic cells.

Specifications

• Accession Number: P10855
• Assay Range: Lot-specific
• Assay Sensitivity: Lot-specific
• Conjugate: HRP
• Product Type: ELISA
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene ID (Entrez): 20302
• Gene Symbol: Ccl3
• Kit Contents: Capture Antibody, Detection Antibody, Protein Standard, HRP-conjugate
• Label or Dye: HRP
• Quantity: 10 x 96 Tests
• Regulatory Status: RUO
• Storage Requirements: Refer to product documentation for component specific storage temperature.
• Target: CCL3 (MIP-1 alpha)
• Test Time: 1 hrs 45 mins
• Total Assay Time: 24 hrs 30 mins