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Midostaurin, MedChemExpress

Product Code. 16486457
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Product Code. 16486457 Supplier Medchem Express Supplier No. HY10230

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Description

MedChemExpress Midostaurin (PKC412; CGP 41251) is an orally active, reversible multi-targeted protein kinase inhibitor. Midostaurin inhibits PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50s ranging from 22-500 nM. Midostaurin also upregulates endothelial nitric oxide synthase (eNOS) gene expression. Midostaurin shows powerful anticancer effects.

Midostaurin (PKC412

Specifications

Chemical Name or Material Midostaurin
CAS 120685-11-2
Color White
Purity Grade Notes Research
Molecular Formula C35H30N4O4
Quantity 5 mg
Synonym PKC412 CGP 41251
Solubility Information DMSO : 50 mg/mL (87.62 mM; Need ultrasonic)
SMILES O=C(C1=CC=CC=C1)N(C)[C@H]2[C@@H](OC)[C@@]3(C)N(C4=C5C=CC=C4)C6=C5C7=C(C(NC7)=O)C8=C6N(C9=CC=CC=C98)[C@@](O3)([H])C2
Molecular Weight (g/mol) 570.64
Formula Weight 570.64
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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