MHC Class I free chain without B2 microglobulin Mouse anti-Human, APC, Clone: A4, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-9958-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15548286

Quantity Price
1 £ 140.02 / 100 tests
Estimated Shipment date
from Supplier 09-05-2017
Add to basket


Description and Specification

Specification

Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Isotype IgG1
Clone A4
Format Conjugated
Antigen MHC Class I free chain without B2 microglobulin
Species Reactivity Human
Host Species Mouse
Applications Flow Cytometry
Primary or Secondary Primary
Conjugate APC
Quantity 100 tests
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.125μg)/test
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.

The A4 monoclonal antibody reacts with the class I human leukocyte antigen (HLA) complex in the absence of β2 microglobulin. There are three class I α-chain genes in humans, called HLA-A, -B and -C. Normally, HLA class I proteins are associated non-covalently with β2 microglobulin (β2M). The function of the HLA class I complex is to present peptides derived from intracellular pathogens, including viral pathogens, on the cell surface to antigen specific CD8+ cytotoxic T cells. Class I HLA is expressed by the majority of nucleated cells.