MHC Class I free chain without B2 microglobulin Mouse anti-Human, APC, Clone: A4, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-9958-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15538286

Quantity Price
1 £ 54.42 / 25 tests
Estimated Shipment date
from Supplier 04-05-2017
Add to basket


Description and Specification

Specification

Isotype IgG1
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Monoclonal or Polyclonal Monoclonal
Host Species Mouse
Species Reactivity Human
Antigen MHC Class I free chain without B2 microglobulin
Clone A4
Conjugate APC
Applications Flow Cytometry
Quantity 25 tests
Primary or Secondary Primary
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Concentration 5μL (0.125μg)/test
Regulatory Status RUO

The A4 monoclonal antibody reacts with the class I human leukocyte antigen (HLA) complex in the absence of β2 microglobulin. There are three class I α-chain genes in humans, called HLA-A, -B and -C. Normally, HLA class I proteins are associated non-covalently with β2 microglobulin (β2M). The function of the HLA class I complex is to present peptides derived from intracellular pathogens, including viral pathogens, on the cell surface to antigen specific CD8+ cytotoxic T cells. Class I HLA is expressed by the majority of nucleated cells.