Invitrogen™ mGluR5 Recombinant Rabbit Monoclonal Antibody (HL2543)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA556788

Product Code. 30276476

Description

mGluR5 Recombinant Monoclonal Antibody for Western Blot, IHC (P)

GRK1 is a member of the guanine nucleotide protein-coupled (G protein) receptor kinase subfamily of Serine/Threonine kinase family. GRK1 phosphorylates rhodopsin and initiates its deactivation. G protein mediated phosphorylation promotes the binding of arrestin, which removes the receptor from the G-protein and terminates the receptor signal chain. GRK1 is farnesylated to promote membrane association. Studies have shown that GRK1 has been shown to be inhibited by recoverin, a Calcium binding protein. Diseases associated with GRK1 protein dysfunction include Oguchi Disease-2 and Hereditary Night Blindness.

Specifications

• Antigen: mGluR5
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P31424, P41594, Q3UVX5
• Gene Symbols: Grm5
• Immunogen: Synthetic peptide encompassing a sequence within the Extracellular domain of human mGluR5. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: HL2543
• Conjugate: Unconjugated
• Gene: Grm5
• Gene Alias: 6430542K11Rik; A830007B11Rik; AI850523; D16Ium24; D16Ium24e; G protein coupled receptor, family C, group 1, member E; G protein-coupled receptor GRM5; G protein-coupled receptor, family C, group 1, member E; Glu5R; Glur5; Glur-5; Glurbeta1; glutamate metabotropic receptor 5; glutamate receptor; glutamate receptor, metabotropic 5; GPRC1A; GPRC1E; GRM 1; GRM 5; GRM1; GRM1 alpha; GRM1A; Grm5; metabotropic 1; metabotropic glutamate receptor (mGluR5); metabotropic glutamate receptor 5; metabotropic glutamate receptor 5b; metabotropic glutamate receptor subtype 5b; metabotropic glutamate receptor type 5; MGC25101; mGlu1; mGlu5; mGluR; mGluR1; mGluR1 alpha; mGluR1A; MGLUR5; mGluR5a; mGluR5b; PPP1R86; protein phosphatase 1, regulatory subunit 86
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 108071, 24418, 2915
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid