Invitrogen™ mGLuR4 Recombinant Rabbit Monoclonal Antibody (6H26L4)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ 702603

Product Code. 16331704

Description

This antibody is predicted to react with Monkey, Pig, Rabbit, Cat. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

The Metabotropic Glutamate Receptor mGluR4/GRM4 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties.

Specifications

• Antigen: mGLuR4
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P31423, Q14833
• Gene Symbols: GRM4
• Immunogen: Peptide corresponding to human mGLUR4 [aa891-aa912].
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry, Western Blot, Immunocytochemistry
• Clone: 6H26L4
• Conjugate: Unconjugated
• Gene: GRM4
• Gene Alias: G protein-coupled receptor GRM4; G protein-coupled receptor, family C, group 1, member D; glutamate metabotropic receptor 4; glutamate receptor; glutamate receptor, metabotropic 4; GPRC1D; GRM4; Metabotropic glutamate receptor 4; mGlu4; MGLUR4
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 24417, 2914
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid