mGluR4 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA533821

Product Code. 15372701

Description

Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Mouse, Rabbit, Pig (100%) Rat, Hamster, Dog (94%) Horse, Opossum (88%).

The Metabotropic Glutamate Receptor mGluR4/GRM4 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties.

Specifications

• Antigen: mGluR4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GRM4
• Gene Alias: G protein-coupled receptor GRM4; G protein-coupled receptor, family C, group 1, member D; glutamate metabotropic receptor 4; glutamate receptor; glutamate receptor, metabotropic 4; GPRC1D; GRM4; Metabotropic glutamate receptor 4; mGlu4; MGLUR4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100347907, 268934, 2914
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q14833, Q68EF4
• Gene Symbols: GRM4
• Immunogen: Synthetic 16 amino acid peptide from C-terminus of human GRM4 / MGLUR4.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Non-human Primate, Rabbit
• Product Type: Antibody
• Isotype: IgG