MFNG Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Thermo Scientific PA561842

Product Code. 15719651

Description

Immunogen sequence: TTRAFHRLRL ELLLDTWVSR TREQTFVFTD SPDKGLQERL GSHLVVTNCS AEHSHPALSC KMAAEFDTFL AS Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 88%.

This gene is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling.

Specifications

• Antigen: MFNG
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MFNG
• Gene Alias: AW546563; beta-1,3-N-acetylglucosaminyltransferase manic fringe; EC 2.4.1.222; manic fringe homolog; Mfng; MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4242
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O00587
• Gene Symbols: MFNG
• Immunogen: Recombinant protein corresponding to Human MFNG
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Research Use Only