Invitrogen™ MFNG Polyclonal Antibody

Sheep Polyclonal Antibody

Brand:  Invitrogen™ PA547834

Product Code. 15588322

Description

Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.

This gene is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling.

Specifications

• Antigen: MFNG
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MFNG
• Gene Alias: AW546563; beta-1,3-N-acetylglucosaminyltransferase manic fringe; EC 2.4.1.222; manic fringe homolog; Mfng; MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
• Host Species: Sheep
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4242
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunoprecipitation, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: O00587
• Gene Symbols: MFNG
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human MFNG Gly37-Arg321.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG