Methyl 4-bromocrotonate, tech. 85%

Product Code.	Quantity	unitSize
11457417	10 g	10g
11467417	50 g	50g
11477417	250 g	250g

Product Code. 11457417 Supplier Thermo Scientific Alfa Aesar Supplier No. A15582.09

Description

CAS: 1117-71-1 | C5H7BrO2 | 179.01 g/mol

It is a useful synthetic intermediate. It was used in the synthesis of irreversible inhibitors of EGFR and HER-2 tyrosine kinases with enhanced antitumor activities.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is a useful synthetic intermediate. It was used in the synthesis of irreversible inhibitors of EGFR and HER-2 tyrosine kinases with enhanced antitumor activities.

Solubility
Slightly soluble in water.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Specifications

Chemical Identifiers

• CAS: 1117-71-1
• Molecular Formula: C5H7BrO2
• Molecular Weight (g/mol): 179.01
• MDL Number: MFCD00000246,MFCD09998308
• InChI Key: RWIKCBHOVNDESJ-NSCUHMNNSA-N
• Synonym: methyl 4-bromocrotonate, e-methyl 4-bromobut-2-enoate, 4-bromocrotonic acid methyl ester, methyl gamma-bromocrotonate, methyl bromocrotonate, methyl 4-bromo-2-butenoate, 2-butenoic acid, 4-bromo-, methyl ester, methyl 4-bromobut-2-enoate, methyl 2e-4-bromobut-2-enoate, crotonic acid, 4-bromo-, methyl ester
• PubChem CID: 5369175
• IUPAC Name: methyl (E)-4-bromobut-2-enoate
• SMILES: COC(=O)\C=C\CBr

• Density: 1.524
• Boiling Point: 83°C to 85°C (13 mmHg)
• Flash Point: 91°C (195°F)
• Linear Formula: BrCH₂CH=CHCO₂CH₃
• Refractive Index: 1.501
• Quantity: 10 g
• UN Number: UN1760
• Beilstein: 1745755
• Solubility Information: Slightly soluble in water.
• Formula Weight: 179.01
• Percent Purity: 85%
• Grade: Technical
• Chemical Name or Material: Methyl 4-bromocrotonate

Safety and Handling

Product Identifier

• Methyl-4-bromocrotonate

Signal Word

• Danger

Hazard Category

• Serious eye damage/eye irritation Category 1
• Skin corrosion/irritation Category 1 C

Hazard Statement

• H314-Causes severe skin burns and eye damage.
• H318-Causes serious eye damage.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

Supplemental information

• MIXTURE LIST-Contain: Methyl-4-bromocrotonate

SDS

RUO – Research Use Only