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Metformin hydrochloride, Tocris Bioscience™

Catalog Number 30001457
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100 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Activator of LKB1/AMPK; antidiabetic agent

Metformin hydrochloride is an antidiabetic agent; lowers plasma glucose levels and improves insulin sensitivity. Inhibits hepatic gluconeogenesis via activation of the LKB1/AMPK pathway. Displays antiproliferative effects in cancer cell lines via inhibition of mitochondrial complex I (MRC-1). Activates the aPKC-CBP pathway in neural precursors to promote neurogenesis. Activates autophagy. Identified by chemoinformatics as targeting human host proteins that interact with SARS-CoV-2.
CAS 1115-70-4
Molecular Formula C4H12ClN5
MDL Number MFCD00012582
Quantity 100 mg
Synonym metformin hydrochloride, 1,1-dimethylbiguanide hydrochloride, metformin hcl, glucophage, riomet, diabefagos, meguan, metformin monohydrochloride, benofomin, denkaform
SMILES [H+].[Cl-].CN(C)C(=N)N=C(N)N
IUPAC Name hydrogen 1-[(diaminomethylidene)amino]-N,N-dimethylmethanimidamide chloride
Molecular Weight (g/mol) 165.63
PubChem CID 14219
Formula Weight 165.62
Percent Purity >98%
Chemical Name or Material Metformin hydrochloride
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