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Eurofins DiscoverX Met Protein, Active

Product Code. 17390294
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Quantity:
10 μg
250 μg
Unit Size:
10µg
250µg
This item is not returnable. View return policy

Product Code. 17390294

Brand: Eurofins DiscoverX 14526M

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This item is not returnable. View return policy

Description

Active, N-terminal His6-tagged recombinant human Met residues 974-end, for use in Kinase Assays.

MET tyrosine kinase is a high-affinity receptor for hepatocyte growth factor/scatter factor. Signaling via this receptor-ligand pair has been shown to affect a wide range of biological activities, including angiogenesis, cellular motility, growth, invasion, and morphogenic differentiation. Mutations in the MET tyrosine kinase receptor have been identified in both hereditary and sporadic forms of papillary renal carcinoma and implicated in tumor growth, invasion, and metastasis.

GenBank J02958. This construct contains the conflicts A1209G and V1290L with respect toGenBank J02958. Both conflicts are reported inGenBank BU595386, BQ315895 and BQ316491.

Specifications

Formulation mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 150 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Molecular Weight (g/mol) 50 kDa
Quantity 250 μg
Species Human
Recombinant Recombinant
Protein Tag N-terminal 6His
Expression System Recombinant enzyme expressed in Sf21 insect cells
Protein Form Truncated
Purity or Quality Grade ≥60%
Protein Met, active
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