Merestinib, MedChemExpress

Product Code.	Quantity	unitSize
16486786	100 mg	100mg
16482677	50 mg	50mg
16459157	5 mg	5mg
16456588	10 mg	10mg

Product Code. 16486786 Supplier Medchem Express Supplier No. HY15514

Description

MedChemExpress Merestinib (LY2801653) is a potent, orally bioavailable c-Met inhibitor (Ki=2 nM) with anti-tumor activities. Merestinib (LY2801653) also has potent activity against MST1R (IC50=11 nM), FLT3 (IC50=7 nM), AXL (IC50=2 nM), MERTK (IC50=10 nM), TEK (IC50=63 nM), ROS1, DDR1/2 (IC50=0.1/7 nM) and MKNK1/2 (IC50=7 nM).

Merestinib (LY2801653) is a potent, orally bioavailable c-Met inhibitor (Ki=2 nM) with anti-tumor activities. Merestinib (LY2801653) also has potent activity against MST1R (IC50=11 nM), FLT3 (IC50=7 nM), AXL (IC50=2 nM), MERTK (IC50=10 nM), TEK (IC50=63 nM), ROS1, DDR1/2 (IC50=0.1/7 nM) and MKNK1/2 (IC50=7 nM).

Specifications

• Chemical Name or Material: Merestinib
• CAS: 1206799-15-6
• Color: White
• Purity Grade Notes: Research
• Molecular Formula: C₃₀H₂₂F₂N₆O₃
• Quantity: 100 mg
• Synonym: LY2801653
• Solubility Information: DMSO : ≥ 32 mg/mL (57.92 mM)
• SMILES: O=C(C1=CC=C(C)N(C2=CC=C(F)C=C2)C1=O)NC3=CC=C(OC4=CC5=C(N(C)N=C5)C=C4C6=CNN=C6)C(F)=C3
• Molecular Weight (g/mol): 552.53
• Formula Weight: 552.53
• Percent Purity: 98.21%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Cancer-Kinase/protease

Research purposes only