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Invitrogen™ MEP1B Polyclonal Antibody
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Product Code. 17190764 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
Product Code. Quantity unitSize
17190764 100 μL 100µL
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Product Code. 17190764

Brand: Invitrogen™ PA5112908

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This item is not returnable. View return policy

Description

Rabbit Polyclonal Antibody

MEP1B Polyclonal Antibody for Western Blot, IHC (P), ELISA

Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MEP1B
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.74 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Mep1b
Gene Accession No. Q16820, Q61847
Gene Alias EC 3.4.24.63; Endopeptidase-2; MEP1B; Mep-1b; meprin 1 beta; meprin A; meprin A subunit beta; meprin A, beta; meprin B; meprin beta; N-benzoyl-L-tyrosyl-p-amino-benzoic acid hydrolase beta subunit; N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta; PABA peptide hydrolase; PPH beta
Gene Symbols Mep1b
Host Species Rabbit
Immunogen Recombinant Human Meprin A subunit beta protein (480-652AA).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17288, 4225
Target Species Human, Mouse
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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