Melatonin, 99+%, Thermo Scientific™

Melatonine, 99%, CAS # 73-31-4, is a hormone usually produced in the pineal gland and released into the blood.

Brand:  Thermo Scientific Alfa Aesar J62452.06

Product Code. 15454829

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Description

• Melatonine is a hormone produced by the pineal gland that shows several biological activities, including the somnolence, sleep-wake cycle, circadian rhythm, stress response, aging, and immunity activities

• It shows antioxidant, autocoid, paracoid, hormonal, anti- inflammatory and anti-apoptotic activities

Applications

• Melatonin shows neurohormonal activity and can upregulate antioxidant enzymes and inhibit rat NOS1

• Melatonin has been reported to be an activator of MEL-1A-R and MEL-1B-R

• The production and secretion of melatonine are dependent on beta-adrenergic receptor function

• During melatonine synthesis, the essential amino acid L-tryptophan is used as a precursor

• This compound inhibits apoptosis in immune cells and neurons, and enhances apoptotic cell death of cancer cells

• It can inhibit proliferation and metastasis of breast cancer cells by modulating Rho-associated kinase protein-1 expression

Chemical Identifiers

• CAS: 73-31-4
• Molecular Weight (g/mol): 232.283
• InChI Key: DRLFMBDRBRZALE-UHFFFAOYSA-N
• PubChem CID: 896
• IUPAC Name: N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide

• Molecular Formula: C13H16N2O2
• MDL Number: MFCD00005655
• Synonym: melatonin, melatonine, n-acetyl-5-methoxytryptamine, circadin, 5-methoxy-n-acetyltryptamine, n-2-5-methoxy-1h-indol-3-yl ethyl acetamide, melatol, melatonex, melovine
• ChEBI: CHEBI:16796
• SMILES: CC(=O)NCCC1=CNC2=C1C=C(C=C2)OC

Specifications

• CAS: 73-31-4
• MDL Number: MFCD00005655
• Beilstein: 205542
• Synonym: melatonin, melatonine, n-acetyl-5-methoxytryptamine, circadin, 5-methoxy-n-acetyltryptamine, n-2-5-methoxy-1h-indol-3-yl ethyl acetamide, melatol, melatonex, melovine
• InChI Key: DRLFMBDRBRZALE-UHFFFAOYSA-N
• IUPAC Name: N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide
• PubChem CID: 896
• Formula Weight: 232.28
• Chemical Name or Material: Melatonin

• Molecular Formula: C13H16N2O2
• Quantity: 5g
• Merck Index: 14,5816
• Solubility Information: Soluble in ethanol to at least 50mg/ml
• SMILES: CC(=O)NCCC1=CNC2=C1C=C(C=C2)OC
• Molecular Weight (g/mol): 232.283
• ChEBI: CHEBI:16796
• Percent Purity: ≥99%