Invitrogen™ MEKK6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5104210

Product Code. 16610665

Description

Antibody detects endogenous levels of total MAP3K6.

Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MEKK6 activates the JNK, but not ERK or p38 kinase pathways.

Specifications

• Antigen: MEKK6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MAP3K6
• Gene Alias: apoptosis signal-regulating kinase 2; ASK2; map3k6; MAPKKK6; MEKK6; MGC125653; MGC20114; mitogen activated protein kinase kinase kinase 6; mitogen-activated protein kinase kinase kinase 6; OTTHUMP00000005063
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 53608, 9064
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O95382, Q9WTR2
• Gene Symbols: MAP3K6
• Immunogen: A synthesized peptide derived from human MAP3K6(Accession O95382), corresponding to amino acid residues A1252-P1288.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG