Invitrogen™ MEK6 Monoclonal Antibody (3H12C8)

Product Code.	Quantity	unitSize
12817832	100 μL	100µL

Product Code. 12817832 Supplier Invitrogen™ Supplier No. MA515808

Description

Mouse Monoclonal Antibody

MA5-15808 targets MAP2K6 in indirect ELISA, FACS, IF, and WB applications and shows reactivity with Human and mouse samples. The MA5-15808 immunogen is purified recombinant fragment of human MAP2K6 expressed in E. Coli. MA5-15808 detects MAP2K6 which has a predicted molecular weight of approximately 38kDa.

MKK6 (MEK6, MAP2K6) is a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. Tissue specificity: Isoform 2 is only expressed in skeletal muscle. Isoform 1, on the other hand, is found in skeletal muscle, heart, and in lesser extent in liver or pancreas.

Specifications

• Antigen: MEK6
• Applications: ELISA, Flow Cytometry, Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: 3H12C8
• Concentration: Conc. Not Determined
• Conjugate: Unconjugated
• Formulation: ascites with 0.03% sodium azide
• Gene: MAP2K6
• Gene Accession No.: P52564, P70236
• Gene Alias: Dual specificity mitogen-activated protein kinase kinase 6; MAP kinase kinase 6; MAP2K6; MAPK/ERK kinase 3; MAPK/ERK kinase 6; MAPKK 3; MAPKK 6; MAPKK3; MAPKK6; MEK 3; MEK 6; MEK3; MEK6; mitogen activated protein kinase kinase 6; mitogen-activated protein kinase kinase 6; MKK3; MKK6; PRKMK3; Prkmk6; protein kinase, mitogen activated, kinase 6; protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6); SAPK kinase 2; SAPK kinase 3; SAPKK2; SAPKK-2; SAPKK3; SAPKK-3; SKK3; Stress-activated protein kinase kinase 3
• Gene Symbols: MAP2K6
• Host Species: Mouse
• Immunogen: Purified recombinant fragment of human MAP2K6 expressed in E. Coli.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 26399, 5608
• Target Species: Human, Mouse
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1