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Invitrogen™ MEK6 Monoclonal Antibody (3H12B9)

Product Code. 12827832
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
12827832 100 μL 100µL
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Product Code. 12827832 Supplier Invitrogen™ Supplier No. MA515809

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Description

Mouse Monoclonal Antibody

MA5-15809 targets MAP2K6 in indirect ELISA, IHC and WB applications and shows reactivity with Human and mouse samples. The MA5-15809 immunogen is purified recombinant fragment of human MAP2K6 expressed in E. Coli. MA5-15809 detects MAP2K6 which has a predicted molecular weight of approximately 38kDa.

MKK6 (MEK6, MAP2K6) is a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. Tissue specificity: Isoform 2 is only expressed in skeletal muscle. Isoform 1, on the other hand, is found in skeletal muscle, heart, and in lesser extent in liver or pancreas.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MEK6
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 3H12B9
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation ascites with 0.03% sodium azide
Gene MAP2K6
Gene Accession No. P52564, P70236
Gene Alias Dual specificity mitogen-activated protein kinase kinase 6; MAP kinase kinase 6; MAP2K6; MAPK/ERK kinase 3; MAPK/ERK kinase 6; MAPKK 3; MAPKK 6; MAPKK3; MAPKK6; MEK 3; MEK 6; MEK3; MEK6; mitogen activated protein kinase kinase 6; mitogen-activated protein kinase kinase 6; MKK3; MKK6; PRKMK3; Prkmk6; protein kinase, mitogen activated, kinase 6; protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6); SAPK kinase 2; SAPK kinase 3; SAPKK2; SAPKK-2; SAPKK3; SAPKK-3; SKK3; Stress-activated protein kinase kinase 3
Gene Symbols MAP2K6
Host Species Mouse
Immunogen Purified recombinant fragment of human MAP2K6 expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26399, 5608
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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