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Invitrogen™ MEK1/MEK2 Recombinant Rabbit Monoclonal Antibody (2I4U3)
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Product Code. 17296993 Shop All Thermo Scientific Products
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100 μL
Unit Size:
100µL
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17296993 100 μL 100µL
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Product Code. 17296993 Supplier Invitrogen™ Supplier No. MA538123

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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: HeLa, HepG2, Jurkat, Mouse brain Immunogen sequence: MPKKKPTPIQ LNPAPDGSAV NGTSSAETNL EALQKKLEEL ELDEQQRKRL EAFLTQKQKV GELKDDDFEK ISELGAGNGG VVFKVSHKPS GLVMARKLIH LEIKPAIRNQ IIRELQVLHE CNSPYIVGFY GAFYSDGEIS ICMEHMDGGS LDQVLKKAGR IPEQILGKVS IAVIKGLTYL REKHKIMHRD VKPSNILVNS RGEIKLCDFG VSGQLIDSMA NSFVGTRSYM SPERLQGTHY SVQSDIWSMG LSLVEMAVGR YPIPPPDAKE LELMFGCQVE GDAAETPPRP RTPGRPLSSY GMDSRPPMAI FELLDYIVNE PPPKLPSGVF SLEFQDFVNK CLIKNPAERA DLKQLMVHAF.

MEK 1 (MAP Kinase Kinase, also known as MKK) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation (Ahn, 1993; Chong et al., 2003). In brain, this pathway also plays a key role in synaptic (Adams and Sweatt, 2002). Activated MEK 1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase (Kyriakis et al., 1991; Seger et al., 1991; Crews et al., 1992).
TRUSTED_SUSTAINABILITY

Specifications

Antigen MEK1/MEK2
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 2I4U3
Concentration 1.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MAP2K2
Gene Accession No. P31938, P36506, P36507, Q01986, Q02750, Q63932
Gene Alias AA589381; CFC3; CFC4; dual specificity mitogen activated protein kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 1; Dual specificity mitogen-activated protein kinase kinase 2; EC 2.7.12.2; ERK activator kinase 1; ERK activator kinase 2; hypothetical protein; hypothetical protein LOC406728; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase 2; MAP kinase/Erk kinase; MAP kinase/Erk kinase 1; Map2k1; Map2k2; MAPK/ERK kinase 1; MAPK/ERK kinase 2; MAPKK 1; MAPKK 2; MAPKK1; MAPKK2; MEK 1; MEK 2; Mek1; MEK-1; Mek2; MEK-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen activated protein kinase kinase 2; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2, p45; mitogen-activated protein kinase kinase type 2; MK2; MKK1; MKK2; MP2K1; PRKMK1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen activated, kinase 2, p45; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); si:ch211-242m18.2; wu:fj56a12; wu:fj61b01; zgc:56557; zgc:56557 protein
Gene Symbols MAP2K1, MAP2K2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-360 of human MEK1/MEK2 (Q02750).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 170851, 26395, 26396, 5604, 5605, 58960
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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