Invitrogen™ MEF2A/MEF2C Recombinant Rabbit Monoclonal Antibody (24GB1280)

Rabbit Recombinant Monoclonal Antibody

Product Code	Brand	Quantity
30274880	Invitrogen™ MA557067	100 μL
30275592	Invitrogen™ MA557068	20 μL

Description

MEF2A/MEF2C Recombinant Monoclonal Antibody for Western Blot, Flow

MEF2A is found in many muscle specific-genes mediating cellular functions in skeletal and cardiac muscle. MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B cells. May also be involved in neurogenesis and in the development of cortical architecture. Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.

Specifications

• Antigen: MEF2A/MEF2C
• Content And Storage: -20°C
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human, Rat
• Gene: MEF2A
• Gene Alias: ADCAD1; C5DELq14.3; DEL5q14.3; mef2; NEDHSIL; RSRFC4; RSRFC9
• Gene Symbols: MEF2A, MEF2C
• Primary or Secondary: Primary
• Purification Method: Affinity chromatography

• Clone: 24GB1280
• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q02078, Q06413, Q2MJT0
• Gene ID (Entrez): 309957, 4205, 4208, 499497
• Immunogen: A synthesized peptide derived from human MEF2A/MEF2C (aa 250-473).
• Product Type: Antibody