Invitrogen™ ME2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA552537

Product Code. 15710491

Description

Immunogen sequence: DGRVFTPGQG NNVYIFPGVA LAVILCNTRH ISDSVFLEAA KALTSQLTDE ELAQGRLYPP LANIQEVSIN IAIKVTEYLY ANKMAFRYPE PEDKAKYVKE RTWRSEYDSL LPDVYEWPES ASSPPV Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 87%.

ME2 encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.

Specifications

• Antigen: ME2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Me2
• Gene Alias: AW120568; D030040L20Rik; malate dehydrogenase; malate dehydrogenase (oxaloacetate-decarboxylating); malic enzyme 2; malic enzyme 2, NAD(+)-dependent, mitochondrial; Me2; NAD-dependent malic enzyme, mitochondrial; NAD-ME; ODS1; pyruvic-malic carboxylase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4200
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P23368
• Gene Symbols: Me2
• Immunogen: Recombinant protein corresponding to Human ME2. Recombinant protein control fragment (Product #RP-88955).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG