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Invitrogen™ ME2 Polyclonal Antibody
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Product Code. 15710491 Shop All Thermo Scientific Products
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100 μL
Unit Size:
100µL
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15710491 100 μL 100µL
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Product Code. 15710491 Supplier Invitrogen™ Supplier No. PA552537

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DGRVFTPGQG NNVYIFPGVA LAVILCNTRH ISDSVFLEAA KALTSQLTDE ELAQGRLYPP LANIQEVSIN IAIKVTEYLY ANKMAFRYPE PEDKAKYVKE RTWRSEYDSL LPDVYEWPES ASSPPV Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 87%.

ME2 encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ME2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Me2
Gene Accession No. P23368
Gene Alias AW120568; D030040L20Rik; malate dehydrogenase; malate dehydrogenase (oxaloacetate-decarboxylating); malic enzyme 2; malic enzyme 2, NAD(+)-dependent, mitochondrial; Me2; NAD-dependent malic enzyme, mitochondrial; NAD-ME; ODS1; pyruvic-malic carboxylase
Gene Symbols Me2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ME2. Recombinant protein control fragment (Product #RP-88955).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4200
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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