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Mdivi 1, Tocris Bioscience™
Selective dynamin inhibitor; attenuates mitochondrial division and apoptosis
£107.35 - £388.44
Chemical Identifiers
| CAS | 338967-87-6 |
|---|---|
| Molecular Formula | C15H10Cl2N2O2S |
| Molecular Weight (g/mol) | 353.217 |
| InChI Key | NZJKEVWTYMOYOR-UHFFFAOYSA-N |
| Synonym | mdivi-1, mdivi 1, 3-2,4-dichloro-5-methoxyphenyl-2-sulfanyl-4 3h-quinazolinone, 3-2,4-dichloro-5-methoxyphenyl-2-sulfanylidene-1h-quinazolin-4-one, 3-2,4-dichloro-5-methoxyphenyl-2,3-dihydro-2-thioxo-4 1h-quinazolinone, mdivi hplc , powder, 3-2,4-dichloro-5-methoxyphenyl-2-mercaptoquinazolin-4 3h-one, 3-2,4-dichloro-5-methoxyphenyl-2-sulfanylquinazolin-4-one, 3-2,4-dichloro-5-methoxyphenyl-2-thioxo-2,3-dihydro-4 1h-quinazolinone |
| PubChem CID | 3825829 |
| IUPAC Name | 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanylidene-1H-quinazolin-4-one |
| SMILES | COC1=C(C=C(C(=C1)N2C(=O)C3=CC=CC=C3NC2=S)Cl)Cl |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18084462
|
Tocris Bioscience
3982/10 |
10 mg |
£107.35
10mg |
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|
18086062
|
Tocris Bioscience
3982/50 |
50 mg |
£388.44
50mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Selective inhibitor of Dnm1 GTPase (IC50 = 1 - 10 μM); attenuates Dnm1- and Drp1-mediated mitochondrial division. Inhibits mitochondrial outer membrane permeabilization (MOMP) and attenuates apoptosis. Inhibits autophagy.Chemical Identifiers
| 338967-87-6 | |
| 353.217 | |
| mdivi-1, mdivi 1, 3-2,4-dichloro-5-methoxyphenyl-2-sulfanyl-4 3h-quinazolinone, 3-2,4-dichloro-5-methoxyphenyl-2-sulfanylidene-1h-quinazolin-4-one, 3-2,4-dichloro-5-methoxyphenyl-2,3-dihydro-2-thioxo-4 1h-quinazolinone, mdivi hplc , powder, 3-2,4-dichloro-5-methoxyphenyl-2-mercaptoquinazolin-4 3h-one, 3-2,4-dichloro-5-methoxyphenyl-2-sulfanylquinazolin-4-one, 3-2,4-dichloro-5-methoxyphenyl-2-thioxo-2,3-dihydro-4 1h-quinazolinone | |
| 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanylidene-1H-quinazolin-4-one |
| C15H10Cl2N2O2S | |
| NZJKEVWTYMOYOR-UHFFFAOYSA-N | |
| 3825829 | |
| COC1=C(C=C(C(=C1)N2C(=O)C3=CC=CC=C3NC2=S)Cl)Cl |
Specifications
| 338967-87-6 | |
| mdivi-1, mdivi 1, 3-2,4-dichloro-5-methoxyphenyl-2-sulfanyl-4 3h-quinazolinone, 3-2,4-dichloro-5-methoxyphenyl-2-sulfanylidene-1h-quinazolin-4-one, 3-2,4-dichloro-5-methoxyphenyl-2,3-dihydro-2-thioxo-4 1h-quinazolinone, mdivi hplc , powder, 3-2,4-dichloro-5-methoxyphenyl-2-mercaptoquinazolin-4 3h-one, 3-2,4-dichloro-5-methoxyphenyl-2-sulfanylquinazolin-4-one, 3-2,4-dichloro-5-methoxyphenyl-2-thioxo-2,3-dihydro-4 1h-quinazolinone | |
| COC1=C(C=C(C(=C1)N2C(=O)C3=CC=CC=C3NC2=S)Cl)Cl | |
| 353.217 | |
| 353.22 | |
| Dynamin Inhibitors |
| C15H10Cl2N2O2S | |
| NZJKEVWTYMOYOR-UHFFFAOYSA-N | |
| 3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanylidene-1H-quinazolin-4-one | |
| 3825829 | |
| >98% |
Safety and Handling
Recommended Storage : Store at -20°C