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Invitrogen™ MD-1 Polyclonal Antibody

Product Code. 12858452
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Quantity:
100 μg
Unit Size:
100µg
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12858452 100 μg 100µg
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Product Code. 12858452 Supplier Invitrogen™ Supplier No. PA520261

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Description

Rabbit Polyclonal Antibody

A suggested positive control is Daudi cell lysate. PA5-20261 can be used with blocking peptide PEP-0376.

MD-1, also known as LY86, is a glycoprotein involved in innate immunity. It is a component of the RP105/MD-1 complex, which is expressed primarily in immune cells like B-cells. MD-1 is structurally similar to MD-2, sharing only 16% sequence identity, yet both are implicated in lipopolysaccharide recognition. The protein contains the ML (MD-2-related lipid-recognition) domain, which is conserved across various species and mediates diverse biological functions by interacting with specific lipids. Structurally, MD-1 is characterized by a beta-rich fold consisting of multiple strands, which is integral to its biological activities. Though MD-1 mainly associates with RP105, its role in lipid recognition suggests functional similarities with proteins such as GM2A and NPC2, implying participation in broader immune signaling pathways.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MD-1
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene LY86
Gene Accession No. O88188, O95711
Gene Alias dJ80N2.1; Ly86; Ly-86; Lymphocyte antigen 86; MD1; MD-1; MD-1, RP105-associated; MMD-1; Protein MD-1; RP1-80N2.1
Gene Symbols LY86
Host Species Rabbit
Immunogen A 15 amino acid peptide from near the center of human MD-1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17084, 291359, 9450
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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