Invitrogen™ MCRS1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA558639

Product Code. 15796511

Description

Immunogen sequence: HPDAFYLART AKALQAHWQL MKQYYLLEDQ TVQPLPKGDQ VLNFSDAEDL IDDSKLKDMR DEVLEHELMV ADRRQKREIR QLEQELHKWQ VLVD Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus (PubMed:11948183). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PubMed:20018852). Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity (PubMed:15044100). Binds to G-quadruplex structures in mRNA (PubMed:16571602). Binds to RNA homopolymer poly(G) and poly(U) (PubMed:16571602). [UniProt].

Specifications

• Antigen: MCRS1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MCRS1
• Gene Alias: 58 kDa microspherule protein; C78274; cell cycle-regulated factor (78 kDa); cell cycle-regulated factor p78; ICP22BP; INO80 complex subunit J; INO80 complex subunit Q; INO80Q; Mcrs1; MCRS2; Microspherule protein 1; MSP58; nucleolar protein; P78
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10445, 300222, 51812
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96EZ8, Q99L90
• Gene Symbols: MCRS1
• Immunogen: Recombinant protein corresponding to Human MCRS1. Recombinant protein control fragment (Product #RP-97876).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG