PeproTech MCP-3 Polyclonal Antibody, PeproTech®, Invitrogen™

Goat Polyclonal Antibody

Product Code	Brand	Quantity
17894203	PeproTech 500-P116G-50UG	50 μg
17843943	PeproTech 500-P116G-100UG	100 μg
17814383	PeproTech 500-P116G-1MG	1 mg

Description

AA Sequence of recombinant protein: QPDGPNASTC CYVKKQKIPK RNLKSYRRIT SSRCPWEAVI FKTKKGMEVC AEAHQKWVEE AIAYLDMKTP TPKP. Preparation: Produced from sera of goats immunized with highly pure Recombinant Murine MCP-3 (CCL7). Anti-Murine MCP-3 (CCL7)-specific antibody was purified by affinity chromatography employing an immobilized Muine MCP-3 (CCL7) matrix. Sandwich ELISA: To detect Murine MCP-3 (CCL7) by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Murine MCP-3 (CCL7) (500-P116GBt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Murine MCP-3 (CCL7). Western Blot: To detect Murine MCP-3 (CCL7) by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Murine MCP-3 (CCL7) is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

This is a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix.

Specifications

• Antigen: MCP-3
• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Host Species: Goat
• Target Species: Mouse
• Gene Accession No.: Q03366
• Gene ID (Entrez): 20306
• Immunogen: E.coli-derived Recombinant Murine MCP-3 (CCL7).
• Purification Method: Antigen affinity chromatography
• Gene: CCL7

• Concentration: 0.1-1.0 mg/mL
• Classification: Polyclonal
• Form: Lyophilized
• Regulatory Status: RUO
• Formulation: PBS with no preservative
• Gene Alias: C-C motif chemokine 7; C-C motif chemokine ligand 7; CCL7; chemokine (C-C motif) ligand 7; chemotactic protein-3; Fic; H-MCP-3; Intercrine/chemokine MARC; marc; Mcp3; MCP-3; MGC138463; MGC138465; Monocyte chemoattractant protein 3; monocyte chemotactic protein 3; NC28; Protein FIC; RANTES/sis homolog; RP23-350G1.4; SCYA6; Scya7; small inducible cytokine A7; small inducible cytokine A7 (monocyte chemotactic protein 3); small-inducible cytokine A7
• Gene Symbols: CCL7
• Primary or Secondary: Primary
• Content And Storage: -20°C