MCM7 Mouse anti-Human, Clone: MCM7/1467, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-59609-100UG

Code produit. 18264145

Description

MCM7 Monoclonal specifically detects MCM7 in Human samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Protein Array, CyTOF-ready.

Spécification

• Antigen: MCM7
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Dilution: Flow Cytometry 0.5-1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml
• Gene Alias: CDC47 homolog, CDC47P85MCM, DNA replication licensing factor MCM7, EC 3.6.4.12, homolog of S. cerevisiae Cdc47, MCM2PNAS146, MCM7 minichromosome maintenance deficient 7 (S. cerevisiae), minichromosome maintenance complex component 7, minichromosome maintenance deficient (S. cerevisiae) 7, minichromosome maintenance deficient 7, P1.1-MCM3, P1CDC47
• Host Species: Mouse
• Molecular Weight of Antigen: 88 kDa
• Quantity: 100 μg
• Research Discipline: Cell Cycle and Replication, Cellular Markers, Core ESC Like Genes, DNA Repair, Stem Cell Markers
• Gene ID (Entrez): 4176
• Target Species: Human
• Form: Purified

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
• Clone: MCM7/1467
• Conjugate: Unconjugated
• Formulation: 0mM PBS with 0.05% BSA with No Preservative
• Gene Symbols: MCM7
• Immunogen: Recombinant human MCM7 protein fragment (aa195-319) (exact sequence is proprietary)
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: The specificity of this monoclonal antibody to its intended target was validated by HuProt Array, containing more than 19,000, full-length human proteins. MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by theMCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Isotype: IgG2a κ

For Research Use Only