Invitrogen™ MCM2 Monoclonal Antibody (11C4)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA549151

Product Code. 17941301

Description

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human CACO-2 whole cell, monkey COS-7 whole cell, human HL-60 whole cell, human HEK293 whole cell, human THP-1 whole cell. IHC: human rectal cancer tissue, human tonsil tissue. ICC/IF: Hela cell. Flow: SiHa cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

MCM2 (Mini chromosome maintenance protein 2) is involved in regulating DNA replication. MCM2 (also called CDCL1, mitotin and BM28), is a human nuclear protein that is crucial in the cell cycle, being involved in the onset of DNA replication and cell division. It is similar to members of the family of early S-phase proteins. MCM2 has been mapped to 3q21. From its localization, CDCL1 became a candidate for an oncogene affected by chromosomal breaks in acute myeloid leukemia (AML).

Specifications

• Antigen: MCM2
• Classification: Monoclonal
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and 0.01mg sodium azide
• Gene Accession No.: P49736
• Gene Symbols: MCM2
• Immunogen: E.coli-derived human MCM2 recombinant protein (Position: S393-R850).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 11C4
• Conjugate: Unconjugated
• Gene: MCM2
• Gene Alias: AA959861; AW476101; BM28; CCNL1; cdc19; CDCL1; cell devision cycle-like 1; cyclin-like 1; D3S3194; DFNA70; DNA replication licensing factor MCM2; Kiaa0030; MCM DNA helicase complex subunit MCM2; Mcm2; Mcmd2; MGC10606; mini chromosome maintenance deficient 2; minichromosome maintenance complex component 2; minichromosome maintenance deficient 2 (mitotin); minichromosome maintenance deficient 2 mitotin; minichromosome maintenance deficient 2 mitotin (S. cerevisiae); Minichromosome maintenance protein 2; Minichromosome maintenance protein 2 homolog; MITOTIN; mKIAA0030; Nuclear protein BM28; YBL023C; YBL0438
• Host Species: Mouse
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4171
• Content And Storage: -20°C
• Form: Lyophilized