missing translation for 'onlineSavingsMsg'
Learn More

MCL-1 Mouse anti-Human, Mouse, Clone: LVUBKM, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9047-80

Code : NEW

Additional Details : Weight : 0.09500kg

 View more versions of this product

Product Code. 15597566

  • £80.50 / 25µg

Estimated Shipment
30-10-2020

Please to purchase this item. Need a web account? Register with us today!


Description

Description

It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. Mcl-1 (Myeloid cell leukemia-1) is a member of the bcl-2 family. The carboxy terminal of Mcl-1 and bcl-2 share significant sequence homology. Expression of Mcl-1 is increased upon exposure of ML-1 cells to various types of DNA damaging agents (e.g. ionizing radiation, ultraviolet radiation, and alkylating drugs) along with increases in GADD45 and Bax and a decrease in bcl-2. Enhanced expression of Mcl-1, prominently associated with mitochondria, complements the continued expression of bcl-2 in ML-1 cells undergoing differentiation. Like bcl-2, Mcl-1 has the capacity to promote cell viability under conditions that otherwise cause apoptosis.
Specifications

Specifications

Mcl-1
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q07820, P97287
bcl-2-like protein 3; bcl-2-related protein EAT/mcl1; EAT; MCL1L; MCL1S; MGC104264; MGC1839; myeloid cell leukemia 1; myeloid cell leukemia ES; myeloid cell leukemia sequence 1 (BCL2-related)
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human, Mouse
Flow Cytometry, Immunohistochemistry (Paraffin)
LVUBKM
Unconjugated
MCL1
Liquid
MCL1
IgG1, kappa
25 μg
4° C
Primary
17210, 4170
Videos
Documents

For Research Use Only.