Invitrogen™ MCFD2 Monoclonal Antibody (294301)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA524000

Product Code. 15533692

Description

In direct ELISAs, approximately 25% cross-reactivity with recombinant mouse SDNSF is observed. In Western blots, no cross-reactivity with recombinant mouse SDNSF is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

Multiple coagulation factor deficiency protein 2 (MCFD2) is localized in the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) through a direct, calcium-dependent interaction with LMAN1. The MCFD2-LMAN1 complex forms a specific cargo receptor for the transport of selected proteins from the endoplasmic reticulum to the Golgi apparatus. Mutations in the MCFD2 gene may cause of factor V and factor VIII combined deficiency (F5F8D). F5F8D is an autosomal recessive human bleeding disorder characterized by the reduction of both clotting proteins.

Specifications

• Antigen: MCFD2
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q8NI22
• Gene Symbols: Mcfd2
• Immunogen: E. coli-derived recombinant human SDNSF/MCFD2 Glu27-Gln146.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunohistochemistry, Western Blot
• Clone: 294301
• Conjugate: Unconjugated
• Gene: Mcfd2
• Gene Alias: 1810021C21Rik; F5F8D; F5F8D2; LMAN1IP; MCFD2; multiple coagulation factor deficiency 2; multiple coagulation factor deficiency protein 2; Multiple coagulation factor deficiency protein 2 homolog; neural stem cell derived neuronal survival protein; neural stem cell-derived neuronal survival protein; Sdnsf; stem cell derived neuronal survival protein
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 90411
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized