Invitrogen™ MCC Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA557933

Product Code. 15775821

Description

Immunogen sequence: VQELVSALER LTKSSEIRHQ QSAEFVNDLK RANSNLVAAY EKAKKKHQNK LKKLESQMMA MVERHETQVR MLKQRIALLE EENSRPHTNE TS Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 99%.

This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: MCC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Mcc
• Gene Alias: colorectal mutant cancer protein; D18Ertd451e; E330037C19; MCC; MCC1; mutated in colorectal cancers; Protein MCC
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4163
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P23508
• Gene Symbols: Mcc
• Immunogen: Recombinant protein corresponding to Human MCC. Recombinant protein control fragment (Product #RP-104125).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG