Invitrogen™ MC1R Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA589029

Product Code. 16507081

Description

Immunogen sequence: LVLMAVLYVH MLARACQHAQ GIARLHKRQR PVHQGFGLKG AVTLTILLGI FFLCWGPFFL HLTLIVLCPE HPTCGCIFKN FNLFLALIIC NAIIDPLIYA FHSQELRRTL KEVLTCSW; Positive Samples: HeLa, Mouse heart, Rat heart; Cellular Location: Cell membrane, Multi-pass membrane protein.

MC1R, a Melanocortin Receptor, mediates the effects of melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH). MSH and its receptor, MC1R, are key regulators of melanogenesis. They control the relative proportions of red pheomelanin and black photoprotective eumelanin in the skin by increasing the production of eumelanin. Non-functional, truncated forms of the receptor lead to lighter coat color in animals. In contrast, constitutively active receptors lead to darker color.

Specifications

• Antigen: MC1R
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Mc1r
• Gene Alias: alpha melanocyte stimulating hormone receptor; CMM5; e; extension recessive yellow; MC1 receptor; MC1R; MC1-R; melanocortin 1 receptor; melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor); melanocortin receptor 1; melanocortin-1 receptor; melanocyte-stimulating hormone receptor; melanotropin receptor; MSHR; MSH-R; Mshra; SHEP2; Tob; tobacco darkening
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 102552838, 17199, 4157
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.69 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: Q01726, Q01727
• Gene Symbols: Mc1r
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-317 of human MC1 Receptor (NP_0023774).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG